Result Statistics
Result statistics
| Number unique A-genes | 1 |
|---|---|
| Number unique B-genes | 1 |
| Number unique A-B gene pairs | 0 |
| Total number of interactions | 7 |
Top Interactions
| A-argument | B-argument | count |
|---|---|---|
| YWHAQ | none | 7 |
A-list mapping 1 0
| input | recognized symbol | mapping type |
|---|---|---|
| 10971 | YWHAQ | Orthology Cluster |
A-List Input Mapping
| input | recognized symbol | mapping type |
|---|---|---|
| 10971 | YWHAQ | Orthology Cluster |
A-List Input Mapping
| input | recognized symbol | mapping type |
|---|
Interaction Partner Distribution A-List (Pie)
Interaction Partner Distribution A-List (Bars)
Most Frequent Interactions
Interactions with Common Partners
Table View
| Gene A Symbol | Gene B Symbol | Gene A Gene ID | Gene B Gene ID | Relation Types | Factuality | Fulltext Match Source | Document ID | Context |
|---|---|---|---|---|---|---|---|---|
| YWHAQ | 10971 | Phosphorylation | none | 9794375 | Furthermore, activation-dependent tyrosine phosphorylation of HS1 was not required for NFAT transcriptional activation. | |||
| YWHAQ | 10971 | Phosphorylation, Regulation | none | 9794375 | Costimulation through CD28 and/or CD2 did not modulate the CD3-dependent phosphorylation of HS1. | |||
| YWHAQ | 10971 | Phosphorylation, Positive_regulation | none | 9794375 | Ligation of CD3 also induces the tyrosine phosphorylation of HS1, a 75-kDa hematopoietic cell-specific intracellular signaling protein of unknown function. | |||
| YWHAQ | 10971 | Phosphorylation | none | 9794375 | Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28. | |||
| YWHAQ | 10971 | Phosphorylation, Positive_regulation | none | 9794375 | Unlike ligation of CD3, stimulation with anti-CD28 mAb or CHO cells expressing the CD28 ligands CD80 or CD86 did not lead to tyrosine phosphorylation of HS1 in Jurkat T cells. | |||
| YWHAQ | 10971 | Phosphorylation, Regulation | none | 9794375 | We have examined changes in HS1 phosphorylation after differential stimulation of CD3, CD2, and CD28 to elucidate its role in T cells and to further delineate the signaling pathways recruited by these receptors. | |||
| YWHAQ | 10971 | Phosphorylation, Positive_regulation | none | 9794375 | Additionally, no tyrosine phosphorylation of HS1 was induced by mitogenic pairs of anti-CD2 mAbs capable of activating the transcription factor NFAT (nuclear factor of activated T cells). |
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Maintenance Notice2024-09-05
GePI currently receives an index rebuild. Until this completes, the interaction database is not complete. GePI can be used but results might be incomplete. This will take 3 to 4 days.